Sapienic acid sodium
Sapienic acid sodium
CAS: 217477-25-3
Molecular Formula: C16H31NaO2
Sapienic acid sodium - Names and Identifiers
| Name | Sapienic acid sodium |
| Synonyms | Sapienic acid sodium |
| CAS | 217477-25-3 |
Sapienic acid sodium - Physico-chemical Properties
| Molecular Formula | C16H31NaO2 |
| Molar Mass | 278.41 |
| In vitro study | Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis , Streptococcus mitis , and Fusobacterium nucleatum but not active against Escherichia coli , Staphylococcus aureus , S. marcescens , P. aeruginosa , Corynebacterium bovis , Corynebacterium striatum , and Corynebacterium jeikeium (MBC > 500 μg/mL). Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h. |
Sapienic acid sodium - Reference Information
| biological activity | Sapienic acid sodium is a fatty acid commonly found in the skin and mucous membranes. Gram-positive and Gram-negative bacteria found in the skin and oral cavity have variable antibacterial activity. Sapienic acid sodium was active against Streptococcus sanguis, the microorganism Streptococcus and Clostridium nucleobacterium with MBC values of 31.3 μg/mL,375.0 μg/mL and 93.8 μg/mL, respectively. |
| target | MBC: 31.3 μg/mL ( Streptococcus sanguinis ), 375.0 μg/mL ( Streptococcus mitis ) and 93.8 μg/mL ( Fusobacterium nucleatum ) |
| in vitro study | Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis , Streptococcus mitis , and Fusobacterium nucleatum but not active against Escherichia coli , Staphylococcus aureus, s marcescens, p aeruginosa , Corynebacterium bovis , Corynebacterium striatum , and Corynebacterium jeikeium (MBC > 500 μg/mL). Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h. |
Last Update：2024-04-09 21:54:55
